Another 2018 study found that Botox helps decrease the number of migraine days by an average of 2 days per month. A 2019 review of research found that 3 months of Botox injection therapy helped BOTOX is indicated for the prophylaxis of headaches in adult patients with chronic migraine (≥15 days per month with headache lasting 4 hours a day or longer). Limitations of Use . Safety and effectiveness have not been established for the prophylaxis of episodic migraine (14 headache days or fewer per month) in seven placebo-controlled studies. Botox injections typically start working one to three days after therapy. The consequences of BOTOX usually begin to appear in a few days after the injection. However, the full effects may not be noticeable for about 1 – 2 weeks, so it is required to serve an adequate amount of time before endeavouring a touch-up treatment. How long does it take for Botox to work? You won’t see any changes straight away. It takes about 2 to 3 days for Botox to start working, and two to three weeks to take full effect. The results will last about 3 to 4 months. Related: What is muscle scraping? Benefits + how to do it at home. Can you exercise after Botox? It normally takes around 4 – 5 days for Botox to have the desired effects. After this point, you should notice a considerable improvement in your appearance and for some people, it can be quite dramatic. The effects will then continue to increase, reaching a peak at around 2 weeks following your first injection. I know Botox takes 7 days to kick in and then its in full effect. Hoping my touch up that I got the other day will loosen a bit as my other side did. I often here that Botox needs to fully set and gets more flexible after the 2 week mark in its finished result. 8 EXPERT ANSWERS. What is Botox? Before understanding how many days it takes for botox to work, let’s first understand what it really is. Botox is derived from Clostridium Botulinum; a bacterium that produces botulinum toxin which when injected in small doses can temporarily paralyze muscles. According to the study, which had a sample size of only 45 people, the time between each touch-up decreased by 22 days: Participants' Botox reportedly lasted a mean of 118 days prior to Botox works on dynamic wrinkles - meaning wrinkles caused when muscles contract. If your "11s" are severe enough that they are also there at rest, then you may have dermal atrophy requiring treatment with a dermal filler such as Juvederm. For static wrinkles - wrinkles at rest - Botox will not be effective during the first few rounds of treatment. December 4, 2018. Botox is one of the most common non-invasive cosmetic procedure performed today. Most patients begin to notice an effect three to five days after their injections, with full results becoming visible after 14 days. When injected for cosmetic purposes, Botox lasts four to six months on average, but you can expect the effects of xfM6u.